Bo-rasaense ba thehile enzyme e ka eketsang sekhahla sa ho bola ha polasetiki ka makhetlo a tšeletseng. Enzyme e fumanoang libaktheria tsa ntlo ea lithōle tse jang lijo tsa polasetiki e sebelisitsoe hammoho le PETase ho akofisa ho bola ha polasetiki.
Ka makhetlo a mararo ts'ebetso ea enzyme e kholo
Sehlopha se thehile enzyme ea tlhaho ea PETase ka laboratoring, e ka potlakisang ho senyeha ha PET ka 20%. Hona joale, sehlopha se tšoanang sa transatlantic se kopantse PETase le "molekane" oa eona (enzyme ea bobeli e bitsoang MHETase) ho hlahisa lintlafatso tse kholo le ho feta: ho kopanya PETase le MHETase feela ho ka eketsa sekhahla sa ho bola ha PET Ho e habeli, le ho rala khokahano lipakeng tsa li-enzyme tse peli ho theha "enzyme e ntle" e kopanyang ketsahalo ena hararo.
Sehlopha se etelletsoe pele ke ramahlale ea qapileng PETase, Moprofesa John McGeehan, motsamaisi oa Setsi sa Enzyme Innovation (CEI) Univesithing ea Portsmouth, le Dr. Gregg Beckham, mofuputsi ea phahameng ho Laboratori ea Naha ea Matla a Tsosolositsoeng (NREL). Naheng ea U.S.
Moprofesa McKeehan o itse: Nna le Greg re bua ka hore na PETase e senya bokaholimo ba polasetiki joang, mme MHETase o e senya hape, ka hona ke tlhaho ho bona hore na re ka e sebelisa hammoho ho etsisa se etsahalang tlhahong. "
Li-enzyme tse peli li sebetsa hammoho
Liteko tsa pele li bontšitse hore li-enzyme tsena li ka sebetsa hantle hammoho, ka hona bafuputsi ba nkile qeto ea ho leka ho li hokela nameng, joalo ka ho kopanya Pac-Man tse peli le ropo.
"Mosebetsi o mongata o entsoe mahlakore ka bobeli a Atlantic, empa re lokela ho etsa boiteko - re thabile ho bona hore enzyme ea rona e ncha ea semela e potlakile ka makhetlo a mararo ho feta enzyme e ikemetseng e iphetotseng ea tlhaho, e bula menyetla e mecha bakeng sa nts'etsopele e tsoelang pele le ntlafatso. " McGeehan o ile a tsoela pele.
Bobeli ba PETase le MHETase-PETase e sa tsoa kopanngoa li ka sebetsa ka ho sila polasetiki ea PET le ho e khutlisetsa mohahong oa eona oa mantlha. Ka tsela ena, lipolasetiki li ka etsoa le ho sebelisoa hape ka ho sa feleng, ka tsela eo ho fokotsa ts'epahalo ea rona ho lisebelisoa tsa khale tse kang oli le khase ea tlhaho.
Moprofesa McKeehan o sebelisitse synchrotron ho Oxfordshire, e sebelisang li-X-ray, tse matla ka makhetlo a limilione tse likete tse 10 ho feta letsatsi, e le microscope, e lekaneng ho shebella liathomo ka bonngoe. Sena se lumelletse sehlopha sa lipatlisiso ho rarolla sebopeho sa 3D sa enzyme ea MHETase, ka hona sa ba fa polane ea limolek'hule ho qala ho rala mekhoa ea enzyme e potlakileng.
Phuputso ena e ncha e kopanya mekhoa ea sebopeho, ea likhomphutha, ea biochemical le bioinformatics ho senola kutloisiso ea limolek'hule ea sebopeho le ts'ebetso ea eona. Phuputso ena ke boiteko bo matla basehlopha bo amang bo-rasaense ba mekhahlelo eohle ea mosebetsi.
