Saynisyahannadu waxay abuureen enzyme kaas oo kordhin kara xaddiga kala-baxa caagagga lix jeer. Enzyme laga helay bakteeriyada guriga qashinka ee quudisa cuntooyinka dhalada balaastigga ah ayaa loo isticmaalay isku darka PETase si loo dedejiyo burburka balaastigga.
Saddex jeer waxqabadka of enzyme super
Kooxda waxay qaabeeyeen enzyme PETase dabiici ah shaybaarka, kaas oo dedejin kara burburka PET qiyaastii 20%. Hadda, isla kooxdii transatlantic waxay isku darsadeen PETase iyo "lammaanahooda" (enzyme-ka labaad ee loo yaqaan MHETase) si ay u soo saaraan xitaa horumarin ballaaran: si fudud isku darka PETase iyo MHETase waxay kordhin kartaa xaddiga kala-baxa PET labalaab, oo qaabee xiriirka ka dhexeeya labada enzymes in la abuuro "super enzyme" oo seddexleynaya hawshan.
Kooxda waxaa hogaaminaya Saynisyahankii naqshadeeyay PETase, Professor John McGeehan, agaasimaha Xarunta Innovation Inzyvation (CEI) ee Jaamacadda Portsmouth, iyo Dr. Gregg Beckham, oo ah cilmi baare sare oo ka tirsan National Labour Energy Energy Laboratory (NREL). Gudaha U.S
Professor McKeehan wuxuu yiri: aniga iyo Greg waxaan kahadleynaa sida PETase ay uxoojiso dusha balaastigga, MHETase ayaa siixukunta, marka waa wax dabiici ah in la arko hadii aan si wada jir ah ugu adeegsan karno si aan ugu ekeysiino waxa ku dhacaya dabeecada. "
Laba enzym ayaa wada shaqeeya
Tijaabooyinkii ugu horreeyay waxay muujiyeen in enzymes-kani runti si wanaagsan u wada shaqeyn karaan, sidaa darteed cilmi-baarayaashu waxay go'aansadeen inay isku dayaan inay ku xirmaan jir ahaan, sida ay isugu xirayaan laba Pac-Man oo leh xarig.
Shaqo badan ayaa laga qabtay labada dhinac ee Atlantic, laakiin waa u qalantaa dadaalka - waxaan ku faraxsanahay inaan aragno in enzyme-keena cusub uu saddex jeer ka dhakhso badan yahay enzyme dabiici ah oo si dabiici ah u kobcay, furitaanka wadooyin cusub oo horumar dheeraad ah leh iyo horumar. " McGeehan ayaa sii waday.
Labadaba PETase iyo MHETase-PETase isku dhafan labaduba waxay ku shaqeyn karaan iyagoo dheefshifaya caaga PET kuna soocelinaya qaabkiisii hore. Sidan oo kale, balaastigga waa la soo saari karaa dibna loo isticmaali karaa si aan dhammaad lahayn, taas oo yareyn doonta ku tiirsanaanta kheyraadka dhulka sida saliidda iyo gaaska dabiiciga ah.
Borofisar McKeehan wuxuu adeegsaday aaladda 'synchrotron' ee Oxfordshire, oo adeegsata raajada, oo 10 bilyan jeer ka xoog badan qorraxda, sida microscope, oo ku filan in lagu ilaaliyo atamyada qofka. Tani waxay u oggolaatay kooxda cilmi-baarista inay xalliyaan qaab-dhismeedka 3D ee 'MHETase enzyme', taas oo ku siinaysa naqshad molikiyuule ah si ay u bilaabaan naqshadeynta nidaamyada enzyme dhakhsaha badan.
Cilmi-baaristaan cusub waxay isku daraysaa qaabdhismeedka, xisaabinta, bayoolajiyeynta iyo hababka bioinformatics si ay u muujiso fahamka molikalka ee qaabdhismeedkeeda iyo shaqadeeda. Cilmi-baaristani waa dadaal kooxeed weyn oo ku lug leh saynisyahannada dhammaan heerarka xirfadeed.
