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Hoʻokumu nā ʻepekema i nā enzyme kūlohelohe i hiki ke wikiwiki i ka decomposition ea e ʻeono mau man

Enlarged font  Narrow font Release date:2020-10-18  Browse number:555
Note: Ua hoʻohana ʻia kekahi enzyme i loko o nā hale bacteria i ʻai i nā papa ʻōmole palika i hui pū ʻia me PETase e hoʻoholomua i ka decomposition o ka ea.

Ua hana nā ʻepekema i kahi enzyme e hiki ke hoʻonui i ka helu o ka palaho popolo i ʻeono mau manawa. Ua hoʻohana ʻia kekahi enzyme i loko o nā hale bacteria i ʻai i nā papa ʻōmole palika i hui pū ʻia me PETase e hoʻoholomua i ka decomposition o ka ea.



ʻEkolu manawa ka hana o super enzyme

Ua hoʻolālā ka kime i kahi enzyme PETase kūlohelohe i loko o ke keʻena hoʻokolohua, kahi e hiki ai i ka wikiwiki o ka palaho o PET ma kahi o 20%. I kēia manawa, ua hui like ka hui transatlantic iā PETase a me kāna "hoapili" (ʻo ka lua o ka enzyme i kapa ʻia ʻo MHETase) e hana i nā hoʻomaikaʻi hou aʻe: ʻo ka hoʻohuihui ʻana iā PETase me MHETase hiki ke hoʻonui i ka helu o ka palaho PET no ka mea ʻelua. e hana i kahi "super enzyme" e pakolu ai kēia hana.

Ua alakaʻi ʻia ke kime e ka ʻepekema nāna i hoʻolālā iā PETase, ʻo Professor John McGeehan, ka luna o ka Center for Enzyme Innovation (CEI) ma ke Kulanui o Portsmouth, a me Kauka Gregg Beckham, he mea noiʻi kiʻekiʻe ma ka National Renewable Energy Laboratory (NREL). I ka U.S.

ʻ saidlelo ʻo Professor McKeehan: Ke kamaʻilio nei māua ʻo Greg e pili ana i ka holoi ʻana o PETase i ka ʻili o ka plastic, a me MHETase e hoʻomāinoino hou iā ia, no laila he mea maʻamau ke ʻike inā hiki iā mākou ke hoʻohana pū iā lākou e hoʻohālike i ka mea i kūlohelohe. "

Hana pū ʻelua mau enzyme

Ua hōʻike ʻia nā hoʻokolohua mua i hiki i kēia mau enzyme ke hana ʻoi aku ka maikaʻi, no laila ua hoʻoholo nā mea noiʻi e hoʻāʻo e hoʻohui iā lākou i ke kino, e like me ka hoʻopili ʻana i ʻelua Pac-Man me kahi kaula.

"Ua nui nā hana i hana ʻia ma nā ʻaoʻao ʻelua o ka ʻAkelanika, akā he waiwai nō ia - ua hauʻoli mākou i ka ʻike ʻana he ʻekolu manawa ka wikiwiki o kā mākou enzyme chimeric hou ma mua o ka hana kūʻokoʻa kūlohelohe, e wehe ana i nā ala hou no ka hoʻomohala hou aku. a me ka hoʻomaikaʻi. " Ua hoʻomau ʻo McGeehan.

Hiki i ka PETase a me ka MHETase-PETase hui hou ke hana me ka hoʻoulu ʻana i ka plastic PET a hoʻihoʻi hou ia i kāna ʻano kumu. I kēia ala, hiki ke hana a hoʻohana hou i nā palolo me ka pau ʻole, a laila e hoʻēmi nei i ko mākou kaukaʻi ʻana i nā kumuwaiwai fossil e like me ka aila a me ke kinoea kūlohelohe.

Ua hoʻohana ʻo Professor McKeehan i kahi synchrotron ma Oxfordshire, kahi e hoʻohana ai i nā kukuna X, he 10 biliona mau manawa i ʻoi aku ka ikaika ma mua o ka lā, ma ke ʻano he microscope, lawa e nānā pono i nā ʻtoma. Ua ʻae kēia i ka hui noiʻi e hoʻonā i ka hanana 3D o ka MHETase enzyme, me ka hāʻawi ʻana iā lākou i kahi blueprint molekiola e hoʻomaka ai i ka hoʻolālā ʻana i nā ʻōnaehana enzyme wikiwiki.

Hoʻohui kēia noiʻi hou i nā hana, computational, biochemical a me nā ʻano bioinformatics e hōʻike i ka ʻike molekole i kāna ʻano a me kāna hana. ʻO kēia noiʻi kahi hana kime nui e pili ana i nā ʻepekema o nā pae hana āpau.
 
 
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